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Can Dulaglutide Modify the Proteomic Signature of CKD Progression? Impacts Beyond Glycemic Control
Dulaglutide may slow CKD progression by modulating inflammatory and fibrotic pathways beyond glucose control.
sophiaambruso
3 hours ago3 min read
Genetic testing (Next Generation Sequencing)—A Sherlock Holmes in discovering the truth of ADPKD
Next-generation sequencing (NGS) is transforming how we diagnose autosomal dominant polycystic kidney disease (ADPKD), particularly in atypical or unclear cases. While most diagnoses rely on imaging and family history, genetic testing offers critical insights into prognosis, mutation type, and family planning. This evolving tool helps unravel diagnostic uncertainty and supports more precise, personalized care in ADPKD.
sophiaambruso
Apr 106 min read
Stopping ADPKD Progression: What We Know & What We Can Do Now
Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disorder caused by PKD1/PKD2 mutations, leading to progressive cyst growth and kidney decline. This blog reviews key disease mechanisms and highlights strategies to slow progression, including strict blood pressure control, tolvaptan therapy, and comprehensive management of modifiable risk factors.
sophiaambruso
Apr 66 min read
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